History's most famous detective made a major comeback this weekend with "Sherlock Holmes", and an opening weekend box office take to the tune of $65 million. Robert Downey Jr. is the current inhabitant of the role, but it was 1939's "The Hounds of Baskervilles" that catapulted the anti-hero that we know today into pop culture lore. In this case Holmes was played by Basil Rathbone, who over the course of his career would play the sleuth 13 times. In "Baskervilles", Holmes uncovers a plot to have a Nobleman killed by a "terrible trained hound".